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9(E)-Octadecenamide

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Catalog No. T38143Cas No. 4303-70-2
Alias FAP-2286, FAP2286

9(E)-Octadecenamide (Elaidamide) is a fatty acid amide and endogenous metabolite that inhibits rat microsomal epoxide hydrolase (mEH) with a Ki of 70 nM.

9(E)-Octadecenamide

9(E)-Octadecenamide

😃Good
Catalog No. T38143Alias FAP-2286, FAP2286Cas No. 4303-70-2
9(E)-Octadecenamide (Elaidamide) is a fatty acid amide and endogenous metabolite that inhibits rat microsomal epoxide hydrolase (mEH) with a Ki of 70 nM.
Pack SizePriceAvailabilityQuantity
10 mg$9335 days
50 mg$39435 days
100 mg$69335 days
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Product Introduction

Bioactivity
Description
9(E)-Octadecenamide (Elaidamide) is a fatty acid amide and endogenous metabolite that inhibits rat microsomal epoxide hydrolase (mEH) with a Ki of 70 nM.
Targets&IC50
mEH:70 nM (Ki)
In vivo
In vivo, 9(E)-Octadecenamide (10 mg/animal) induces physiological sleep in rats.[1]
SynonymsFAP-2286, FAP2286
Chemical Properties
Molecular Weight281.48
FormulaC18H35NO
Cas No.4303-70-2
SmilesC(C/C=C/CCCCCCCC)CCCCCC(N)=O
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 1.5 mg/mL (5.33 mM), Sonication is recommended.
DMF:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.78 mM), Sonication is recommended.
DMF:PBS (pH 7.2)(1:1): 0.4 mg/mL (slightly soluble), Sonication is recommended.
Solution Preparation Table
DMF:PBS (pH 7.2) (1:1)/DMF
1mg5mg10mg50mg
1 mM3.5527 mL17.7633 mL35.5265 mL177.6325 mL
DMF
1mg5mg10mg50mg
5 mM0.7105 mL3.5527 mL7.1053 mL35.5265 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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