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Anti-IGF1 LR3 Antibody (7E748) (Synonyms: Mgf, insulin-like growth factor 1 (somatomedin C), IGF‑I, IGF-I, I...)

Catalog No. TMAY-01005 Copy Product Info
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Anti-IGF1 LR3 Antibody (7E748) is a Mouse antibody targeting IGF1 LR3. Anti-IGF1 LR3 Antibody (7E748) can be used in ELISA.

Anti-IGF1 LR3 Antibody (7E748)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01005
Synonyms Mgf, insulin-like growth factor 1 (somatomedin C), IGF‑I, IGF-I, IGFI, IGF1A, IGF-1

Anti-IGF1 LR3 Antibody (7E748) is a Mouse antibody targeting IGF1 LR3. Anti-IGF1 LR3 Antibody (7E748) can be used in ELISA.

Anti-IGF1 LR3 Antibody
(7E748)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IGF1 LR3 Antibody (7E748) is a Mouse antibody targeting IGF1 LR3. Anti-IGF1 LR3 Antibody (7E748) can be used in ELISA.
SynonymsMgf, insulin-like growth factor 1 (somatomedin C), IGF‑I, IGF-I, IGFI, IGF1A, IGF-1
Ig Type
Mouse IgG1
Clone
7E748
Reactivity
Human
Specificity
Human IGF1
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IGF1 LR3 (rh IGF1 LR3; TMPY-04942; P05019-1; Gly49-Ala118,E51R). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ), and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also about enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness, and mental retardation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IGF1 LR3 Protein (TMPY-04942)
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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