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SID 7969543

Name: SID 7969543
Brand: TargetMol
SKU: T23354
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23354Cas No. 868224-64-0

Alias SID7969543

SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.

SID 7969543

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Purity: 98.94%

Catalog No. T23354Alias SID7969543Cas No. 868224-64-0

SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$39	In Stock	In Stock
5 mg	$89	In Stock	In Stock
10 mg	$127	In Stock	In Stock
25 mg	$255	In Stock	In Stock
50 mg	$428	In Stock	In Stock
100 mg	$687	-	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.94%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.
Targets&IC50	SF1:760 nM, SFRE:30 nM
In vitro	SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. In a functional activity assay, SID 7969543 was used to evaluate the response of HEK 293T cells co-transfected with a plasmid encoding full-length SF-1 and a vector expressing the fluorokinase gene under the control of five tandem natural SF-1 response elements (SFRE). SID 7969543 has an IC50 of 30 nM and significantly inhibits SF-1-induced fluorokinase expression. [1]
Synonyms	SID7969543

Chemical Properties

Molecular Weight	452.46
Formula	C₂₄H₂₄N₂O₇
Cas No.	868224-64-0
Smiles	O=C(OCC)C(OC1=CC=CC=2C(=O)N(C=CC12)CC(=O)NC3=CC=C4OCCOC4=C3)C
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (88.41 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 1.5 mg/mL (3.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2101 mL	11.0507 mL	22.1014 mL	110.5070 mL
5 mM	0.4420 mL	2.2101 mL	4.4203 mL	22.1014 mL
10 mM	0.2210 mL	1.1051 mL	2.2101 mL	11.0507 mL
20 mM	0.1105 mL	0.5525 mL	1.1051 mL	5.5254 mL
50 mM	0.0442 mL	0.2210 mL	0.4420 mL	2.2101 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc