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SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $39 | In Stock | In Stock | |
| 5 mg | $89 | In Stock | In Stock | |
| 10 mg | $127 | In Stock | In Stock | |
| 25 mg | $255 | In Stock | In Stock | |
| 50 mg | $428 | In Stock | In Stock | |
| 100 mg | $687 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $98 | In Stock | In Stock |
| Description | SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research. |
| Targets&IC50 | SF1:760 nM, SFRE:30 nM |
| In vitro | SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. In a functional activity assay, SID 7969543 was used to evaluate the response of HEK 293T cells co-transfected with a plasmid encoding full-length SF-1 and a vector expressing the fluorokinase gene under the control of five tandem natural SF-1 response elements (SFRE). SID 7969543 has an IC50 of 30 nM and significantly inhibits SF-1-induced fluorokinase expression. [1] |
| Synonyms | SID7969543 |
| Molecular Weight | 452.46 |
| Formula | C24H24N2O7 |
| Cas No. | 868224-64-0 |
| Smiles | O=C(OCC)C(OC1=CC=CC=2C(=O)N(C=CC12)CC(=O)NC3=CC=C4OCCOC4=C3)C |
| Relative Density. | no data available |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (88.41 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 1.5 mg/mL (3.32 mM), Sonication is recommeded. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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