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TAT

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Catalog No. TP1809Cas No. 191936-91-1

TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating peptide demonstrates significant potential in biotechnological applications.

TAT
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TAT

🥰Excellent
Catalog No. TP1809Cas No. 191936-91-1
TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating peptide demonstrates significant potential in biotechnological applications.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$44In StockIn Stock
5 mg$139In StockIn Stock
10 mg$208In StockIn Stock
25 mg$353In StockIn Stock
50 mg$525In StockIn Stock
100 mg$747In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:>99.99%
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Product Introduction

Bioactivity
Description
TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating peptide demonstrates significant potential in biotechnological applications.
In vitro
TAT (YGRKKRRQRRR), corresponding to amino acids 47-57 of the HIV-1 TAT protein, embodies the positively charged protein transduction domain (TAT-PTD) that efficiently permeates the plasma membrane of live cells. This characteristic is utilized for intracellular delivery of proteins, drugs, and genes. Owing to its TAT-PTD, TAT (YGRKKRRQRRR; TAT-PTD) can traverse the cell's hydrophobic lipid bilayer through passive diffusion[1].
Chemical Properties
Molecular Weight1559.83
FormulaC64H118N32O14
Cas No.191936-91-1
Smiles[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N
Relative Density.1.54 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
SequenceTyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg
Sequence ShortYGRKKRRQRRR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

TATPeptideInhibitorinhibitHuman immunodeficiency virusHIVProteaseHIV-1HIV ProteaseHIV
Related Tags: buy TAT | purchase TAT | TAT cost | order TAT | TAT chemical structure | TAT in vitro | TAT formula | TAT molecular weight
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