Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-BCL-XL Antibody (2A140) (Synonyms: PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BC...)
Catalog No. TMAH-00111 Copy Product Info
🥰Excellent
Anti-BCL-XL Antibody (2A140) is an antibody targeting BCL-XL. Anti-BCL-XL Antibody (2A140) can be used in ELISA,IHC,WB.
Anti-BCL-XL Antibody (2A140)
Copy Product Info🥰Excellent
Catalog No. TMAH-00111
Synonyms PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L
Anti-BCL-XL Antibody (2A140) is an antibody targeting BCL-XL. Anti-BCL-XL Antibody (2A140) can be used in ELISA,IHC,WB.
Anti-BCL-XL Antibody
(2A140)
(2A140)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-BCL-XL Antibody (2A140) is an antibody targeting BCL-XL. Anti-BCL-XL Antibody (2A140) can be used in ELISA,IHC,WB. |
| Synonyms | PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L |
| Ig Type | Rabbit IgG |
| Clone | 2A140 |
| Reactivity | Human, Mouse, Rat |
| Verified Activity | 1. Western Blot -Positive WB detected in: K562 whole cell lysate, Hela whole cell lysate, NIH/3T3 whole cell lysate, Rat Brain whole cell lysate, Mouse Brain whole cell lysate -All lanes: Bcl-XL antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 27, 19, 26 kDa -Observed band size: 30 kDa 2. IHC image of TMAH-00111 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. |
| Tissue Specificity | Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release. Isoform Bcl-X(S) promotes apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Bcl-XL |
| Antigen Species | Human |
| Gene Name | BCL2L1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cell biology, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-BCL-XL Antibody (2A140) | purchase Anti-BCL-XL Antibody (2A140) | Anti-BCL-XL Antibody (2A140) cost | order Anti-BCL-XL Antibody (2A140)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.