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Bersanlimab (Synonyms: BI-505)

Catalog No. T76927 Copy Product Info
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Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma.

Bersanlimab

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Catalog No. T76927
Synonyms BI-505

Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma.

Bersanlimab
Cas No. 1987854-08-9
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$289In StockIn Stock
5 mg$689In StockIn Stock
10 mg$1,070-In Stock
25 mg$1,590-In Stock
50 mg$2,150-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma.
In vitro
Bersanlimab(BI-505) induces dose-dependent expression of ICAM-1 and programmed cell death (PCD) in Ramos, Raji, and Daudi lymphoma cells, with a dosage range spanning from 1 ng/mL to 1000 μg/mL [1].
In vivo
Bersanlimab (BI-505), administered at a dose of 20 mg/kg via intraperitoneal injection twice a week for a continuous period of 21 days, significantly reduces tumor growth and prolongs the survival of animals [1].
SynonymsBI-505
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetICAM1/CD54
Chemical Properties
Molecular Weight144.22 kDa
Cas No.1987854-08-9
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.

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