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CCK (27-33) (non-sulfated)

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Catalog No. T37206Cas No. 47910-79-2

CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.

CCK (27-33) (non-sulfated)
Other Forms of CCK (27-33) (non-sulfated):

CCK (27-33) (non-sulfated)

😃Good
Catalog No. T37206Cas No. 47910-79-2
CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.
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1 mg$21835 days35 days
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Product Introduction

Bioactivity
Description
CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.
Chemical Properties
Molecular Weight948.12
FormulaC45H57N9O10S2
Cas No.47910-79-2
Sequence ShortYMGWMDF-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Formic Acid: 1 mg/mL (1.05 mM), Sonication is recommended.
Solution Preparation Table
Formic Acid
1mg5mg10mg50mg
1 mM1.0547 mL5.2736 mL10.5472 mL52.7359 mL

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Keywords

CCK (27 33) (non sulfated)CCKnon-sulfatedCCK (2733) (nonsulfated)
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