Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme activity and reduction of PAR protein levels. Additionally, it suppresses CDK12 expression [1].
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Description | Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme activity and reduction of PAR protein levels. Additionally, it suppresses CDK12 expression [1]. |
Molecular Weight | 556.63 |
Formula | C31H33FN6O3 |
CAS No. | 2245272-16-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antitumor agent-104 2245272-16-4 Chromatin/Epigenetic DNA Damage/DNA Repair PARP inhibitor inhibit