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Coenzyme FO

Catalog No. T37978 Copy Product Info
Purity: 99.86%
🥰Excellent
TargetMol
Coenzyme FO, a deazaflavin chromophore, is essential as a hydride acceptor/donor in the central methanogenic pathway [1][2].

Coenzyme FO

Copy Product Info
🥰Excellent
TargetMol
Catalog No. T37978

Coenzyme FO, a deazaflavin chromophore, is essential as a hydride acceptor/donor in the central methanogenic pathway [1][2].

Coenzyme FO
Cas No. 37333-48-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$148In StockIn Stock
5 mg$363In StockIn Stock
10 mg$539In StockIn Stock
25 mg$873In StockIn Stock
50 mg$1,180In StockIn Stock
100 mg$1,620-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.86%
ee:96.1%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Coenzyme FO, a deazaflavin chromophore, is essential as a hydride acceptor/donor in the central methanogenic pathway [1][2].
In vitro
Coenzyme FO is an intermediate in the synthesis of F420, while coenzyme F420 is a low redox potential electron carrier involved in energy metabolism, NADP reduction, oxygen detoxification, and sulfite reduction in methanogenic and certain non-methanogenic archaea. F420 can be reduced by F420-dependent hydrogenase and assists in resisting the antimicrobial action of macrophages in Mycobacterium tuberculosis[3].
Chemical Properties
Molecular Weight363.32
FormulaC16H17N3O7
Cas No.37333-48-5
SmilesC([C@@H]([C@@H]([C@@H](CO)O)O)O)N1C=2C(=CC=3C1=CC(O)=CC3)C(=O)NC(=O)N2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 1 mg/mL (insoluble)
DMSO: 8 mg/mL (22.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7524 mL13.7620 mL27.5239 mL137.6197 mL
5 mM0.5505 mL2.7524 mL5.5048 mL27.5239 mL
10 mM0.2752 mL1.3762 mL2.7524 mL13.7620 mL
20 mM0.1376 mL0.6881 mL1.3762 mL6.8810 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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