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Anti-VCAM1 Monoclonal Antibody (Synonyms: Vascular cell adhesion protein 1, INCAM-100)

Catalog No. TMAZ-0012 Copy Product Info
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Anti-VCAM1 Monoclonal Antibody is a humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody can be used in ELISA,FCM.

Anti-VCAM1 Monoclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAZ-0012
Synonyms Vascular cell adhesion protein 1, INCAM-100

Anti-VCAM1 Monoclonal Antibody is a humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody can be used in ELISA,FCM.

Anti-VCAM1 Monoclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
25 μg$19612 days12 days
50 μg$23612 days12 days
100 μg$33012 days12 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VCAM1 Monoclonal Antibody is a humanized rabbit antibody targeting VCAM1. Anti-VCAM1 Monoclonal Antibody can be used in ELISA,FCM.
SynonymsVascular cell adhesion protein 1, INCAM-100
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of VCAM1 overexpressed 400F cells with TMAZ-0012, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
Recommended Dose
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSingle-pass type I membrane
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of VCAM1 protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in PBS.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundCell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed: 31310649). Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins (PubMed: 10209034). During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration (PubMed: 22970700). Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation (PubMed: 35210567)
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Biotin
Antibody Types Available
2
Antigen Details
Immunogen
VCAM1
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Immunology Research
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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