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Haemoglobin is an iron-containing oxygen-binding protein and a globin containing haem, present in red blood cells, capable of transporting oxygen from the lungs to tissues. Haemoglobin is a multifunctional molecule involved in numerous enzymatic catalysis, nitric oxide metabolism, pH regulation, and maintaining redox balance, amongst other functions.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 mg | $31 | - | In Stock | |
| 1 g | $49 | - | In Stock |
| Description | Haemoglobin is an iron-containing oxygen-binding protein and a globin containing haem, present in red blood cells, capable of transporting oxygen from the lungs to tissues. Haemoglobin is a multifunctional molecule involved in numerous enzymatic catalysis, nitric oxide metabolism, pH regulation, and maintaining redox balance, amongst other functions. |
| In vitro | Hemoglobin (1-50 μM) treatment of HepG2 cells for 6 hours significantly increased α1-microglobulin levels and elevated reactive oxygen species content. [3] |
| In vivo | In the lipopolysaccharide (LPS)-induced rat endotoxemia model, Hemoglobin (300 mg/kg) was intravenously administered 16 hours before LPS injection. At 24 hours post-LPS injection, Hemoglobin significantly alleviated neutrophil alveolitis, increased the expression and activity of heme oxygenase-1 (HO-1) in rat lung tissues, and improved the survival rate of the rats. |
| Cas No. | 9008-02-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | H2O: 15 mg/mL, Sonication is recommended. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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