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Belantamab mafodotin
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Catalog No. T77903Cas No. 2050232-20-5
Alias GSK2857916, GSK 2857916, Belantamab mafodotin-blm
Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate targeting B-cell maturation antigen (BCMA) that enhances immune cell infiltration and activation within tumors and delays tumor growth. It is used in studies of multiple myeloma.
Belantamab mafodotin
Belantamab mafodotin
😃Good
Catalog No. T77903Alias GSK2857916, GSK 2857916, Belantamab mafodotin-blmCas No. 2050232-20-5
Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate targeting B-cell maturation antigen (BCMA) that enhances immune cell infiltration and activation within tumors and delays tumor growth. It is used in studies of multiple myeloma.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $778 | - | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $1,830 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.14% (SEC-HPLC)
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| Description | Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate targeting B-cell maturation antigen (BCMA) that enhances immune cell infiltration and activation within tumors and delays tumor growth. It is used in studies of multiple myeloma. |
| Targets&IC50 | BCMA (human):1 nM (Kd) |
| In vitro | Belantamab mafodotin is an immune conjugate (ADC) that targets B cell maturation antigens. The Kd value of Belantamab mafodotin binding human BCMA protein was 1 nM. Belantamab mafodotin induces G2/M phase arrest in multiple myeloma cells in a dose - and time-dependent manner. [1] |
| In vivo | Belantamab mafodotin significantly improved survival in mice with OPM2 tumors. [1] |
| Synonyms | GSK2857916, GSK 2857916, Belantamab mafodotin-blm |
| Reactivity | Human |
| Verified Activity | Immobilized Human BCMA-ECD-His at 2 μg/mL can bind Belantamab mafodotin. The EC50 is 0.02634 μg/mL |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | MMAF |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF17/BCMA/CD269 |
| Molecular Weight | 146.06 kDa |
| Cas No. | 2050232-20-5 |
| Isotype | IgG1 kappa-McMMAF |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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