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Belantamab mafodotin
(Synonyms: GSK2857916, GSK 2857916, Belantamab mafodotin-blm) Copy Product Info
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Synonyms: GSK2857916, GSK 2857916, Belantamab mafodotin-blm
Catalog No. T77903 Copy Product Info
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Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate targeting B-cell maturation antigen (BCMA) that enhances immune cell infiltration and activation within tumors and delays tumor growth. It is used in studies of multiple myeloma.
Belantamab mafodotin
Cas No. 2050232-20-5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $778 | - | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $1,830 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.14% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
Antibody Information
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| Description | Belantamab mafodotin (GSK2857916) is an antibody-drug conjugate targeting B-cell maturation antigen (BCMA) that enhances immune cell infiltration and activation within tumors and delays tumor growth. It is used in studies of multiple myeloma. |
| Targets & IC50 | BCMA (human):1 nM (Kd) |
| In vitro | Belantamab mafodotin is an immune conjugate (ADC) that targets B cell maturation antigens. The Kd value of Belantamab mafodotin binding human BCMA protein was 1 nM. Belantamab mafodotin induces G2/M phase arrest in multiple myeloma cells in a dose - and time-dependent manner. [1] |
| In vivo | Belantamab mafodotin significantly improved survival in mice with OPM2 tumors. [1] |
| Synonyms | GSK2857916, GSK 2857916, Belantamab mafodotin-blm |
| Reactivity | Human |
| Verified Activity | Immobilized Human BCMA Protein (ECD, His) at 2 μg/mL can bind Belantamab mafodotin. The EC50 is 0.02634 μg/mL  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | MMAF |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF17/BCMA/CD269 |
| Molecular Weight | 146.06 kDa |
| Cas No. | 2050232-20-5 |
| Isotype | IgG1 kappa-McMMAF |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Belantamab mafodotin in vivo | Belantamab mafodotin in vitro | Belantamab mafodotin molecular weight
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