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Anti-NME1 Antibody (1A526)

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Catalog No. TMAY-01936
Alias NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD

Anti-NME1 Antibody (1A526) is a Rabbit antibody targeting NME1. Anti-NME1 Antibody (1A526) can be used in ELISA.

Anti-NME1 Antibody (1A526)

Anti-NME1 Antibody (1A526)

😃Good
Catalog No. TMAY-01936Alias NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD
Anti-NME1 Antibody (1A526) is a Rabbit antibody targeting NME1. Anti-NME1 Antibody (1A526) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-NME1 Antibody (1A526) is a Rabbit antibody targeting NME1. Anti-NME1 Antibody (1A526) can be used in ELISA.
AliasNME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD
Ig Type
Monoclonal Rabbit IgG
Clone
1A526
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human NME1 / NDKA (rh NME1 / NDKA; TMPY-04467; NP_000260.1; Ala2-Glu152).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundNME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as CKI and Aurora-A/STK15. The second group of proteins acts as downstream effectors for the regulation of specific gene transcriptions, GTP-binding protein functions, and signal transduction in the Erk signal cascade. The third group of proteins can be classified as bi-directionally influencing binding partners of NM23-H1. As a result, the interactions with NM23-H1 and binding partners have implications in the biochemical characterization involved in metastasis and tumorigenesis. NDKA is increased in human postmortem cerebrospinal fluid (CSF), a model of global brain insult, suggesting that measurement in CSF and, more importantly, in plasma may be useful as a biomarker of stroke. Additionally, NM23-H1 significantly reduces metastasis without effects on primary tumor size and was the first discovered metastasis suppressor gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human NME1 / NDKA protein (TMPY-04467)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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