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5-Methylresorcinol monohydrate
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Catalog No. T85490Cas No. 6153-39-5
Alias Orcinol monohydrate
5-Methylresorcinol monohydrate (Orcinol monohydrate) serves as a tyrosinase inhibitor and demonstrates cytotoxic properties. Additionally, it is an orally active anxiolytic agent that can cross the blood-brain barrier [1] [2].
5-Methylresorcinol monohydrate
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Catalog No. T85490Alias Orcinol monohydrateCas No. 6153-39-5
5-Methylresorcinol monohydrate (Orcinol monohydrate) serves as a tyrosinase inhibitor and demonstrates cytotoxic properties. Additionally, it is an orally active anxiolytic agent that can cross the blood-brain barrier [1] [2].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 5-Methylresorcinol monohydrate (Orcinol monohydrate) serves as a tyrosinase inhibitor and demonstrates cytotoxic properties. Additionally, it is an orally active anxiolytic agent that can cross the blood-brain barrier [1] [2]. |
| In vitro | 5-Methylresorcinol monohydrate (Orcinol monohydrate), administered at concentrations of 100, 200, and 500 µM over periods of 24 and 72 hours, exhibited cytotoxic effects on B16 and Hs68 cell lines. According to the Cell Cytotoxicity Assay, it resulted in an inhibition rate of 101.7% in Hs68 cells at 24 hours and 104.4% in B16 cells at 72 hours. |
| In vivo | 5-Methylresorcinol monohydrate, administered orally at doses of 2.5 and 5 mg/kg, exhibits anti-anxiety properties without producing sedation [2]. In studies using male CD-1 mice weighing 18-22 g [2], this compound increased both the duration and frequency of open arm entries in the elevated plus-maze test, as well as the number of head-dips in the hole-board test. Importantly, it did not significantly alter the locomotor activity in the open-field test. |
| Synonyms | Orcinol monohydrate |
| Molecular Weight | 142.15 |
| Formula | C7H10O3 |
| Cas No. | 6153-39-5 |
| Smiles | O.OC=1C=C(O)C=C(C1)C |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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