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EJMC-1

Name: EJMC-1
Brand: TargetMol
SKU: T60054
Price: 88 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60054Cas No. 397281-20-8

Alias N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide

EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.

EJMC-1

🥰Excellent

Purity: 98.38%

Catalog No. T60054Alias N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideCas No. 397281-20-8

EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$88	-	In Stock
5 mg	$222	-	In Stock
10 mg	$316	-	In Stock
25 mg	$461	-	In Stock
50 mg	$630	-	In Stock
100 mg	$852	-	In Stock
200 mg	$1,150	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.38%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.
Synonyms	N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide

Chemical Properties

Molecular Weight	374.8
Formula	C₁₇H₁₁ClN₂O₄S
Cas No.	397281-20-8
Smiles	Oc1ccc(NS(=O)(=O)c2ccc3NC(=O)c4cccc2c34)cc1Cl

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (266.8 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6681 mL	13.3404 mL	26.6809 mL	133.4045 mL
5 mM	0.5336 mL	2.6681 mL	5.3362 mL	26.6809 mL
10 mM	0.2668 mL	1.3340 mL	2.6681 mL	13.3404 mL
20 mM	0.1334 mL	0.6670 mL	1.3340 mL	6.6702 mL
50 mM	0.0534 mL	0.2668 mL	0.5336 mL	2.6681 mL
100 mM	0.0267 mL	0.1334 mL	0.2668 mL	1.3340 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc