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Anti-CD157 Antibody (5L480)
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Catalog No. TMAY-00199
Alias bone marrow stromal cell antigen 1
Anti-CD157 Antibody (5L480) is a Mouse antibody targeting CD157. Anti-CD157 Antibody (5L480) can be used in FCM.
Anti-CD157 Antibody (5L480)
Anti-CD157 Antibody (5L480)
😃Good
Catalog No. TMAY-00199Alias bone marrow stromal cell antigen 1
Anti-CD157 Antibody (5L480) is a Mouse antibody targeting CD157. Anti-CD157 Antibody (5L480) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD157 Antibody (5L480) is a Mouse antibody targeting CD157. Anti-CD157 Antibody (5L480) can be used in FCM. |
| Alias | bone marrow stromal cell antigen 1 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5L480 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human BST1(CD157) expression on human whole blood monocytes. Cells were stained with purified anti-Human BST1(CD157), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD157/BST1 (rh CD157/BST1; TMPY-00968; NP_004325.2; Met1-Lys292). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2−) production in the human U937 myeloid line. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD157/BST1 Protein (TMPY-00968) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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