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Thymidylate Kinase Inhibitor, YMU1

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Catalog No. T8864Cas No. 902589-96-2

YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.

Thymidylate Kinase Inhibitor, YMU1

Thymidylate Kinase Inhibitor, YMU1

😃Good
Purity: 98.06%
Catalog No. T8864Cas No. 902589-96-2
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$43In StockIn Stock
10 mg$68In StockIn Stock
25 mg$137In StockIn Stock
50 mg$220In StockIn Stock
100 mg$355In StockIn Stock
200 mg$495-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.06%
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COA HNMR LCMS HPLC

Product Introduction

Bioactivity
Description
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.
Chemical Properties
Molecular Weight378.45
FormulaC17H22N4O4S
Cas No.902589-96-2
SmilesO=C1C=2C(SN1CC(=O)N3CCN(C(OCC)=O)CC3)=NC(C)=CC2C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (13.21 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6424 mL13.2118 mL26.4236 mL132.1178 mL
5 mM0.5285 mL2.6424 mL5.2847 mL26.4236 mL
10 mM0.2642 mL1.3212 mL2.6424 mL13.2118 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

YMU-1YMU1YMU 1Thymidylate Kinase Inhibitor, YMU-1Thymidylate Kinase Inhibitor, YMU1InhibitorinhibithTMPK
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