Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 233.00 | |
5 mg | 5 days | $ 297.00 | |
25 mg | 6-8 weeks | $ 916.00 | |
50 mg | 6-8 weeks | $ 1,190.00 | |
100 mg | 6-8 weeks | $ 1,860.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 318.00 |
Description | EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1]. |
In vitro | EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1].EMI56 (10, 15, 20 μM; 2 h of treatment) strongly inhibits total EGFR levels, activation and downstream signaling in PC9 EGFR ex19del/T790M/C797S cells[1]. |
Molecular Weight | 348.4 |
Formula | C21H20N2O3 |
CAS No. | 2414374-41-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (143.51 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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EMI56 2414374-41-5 EMI 56 EMI-56 inhibitor inhibit