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Anti-Dectin-1 Antibody (1X697)

🥰Excellent
Catalog No. TMAY-03186

Anti-Dectin-1 Antibody (1X697) is a Rabbit antibody targeting Dectin-1. Anti-Dectin-1 Antibody (1X697) can be used in ELISA.

Anti-Dectin-1 Antibody (1X697)

Anti-Dectin-1 Antibody (1X697)

🥰Excellent
Catalog No. TMAY-03186
Anti-Dectin-1 Antibody (1X697) is a Rabbit antibody targeting Dectin-1. Anti-Dectin-1 Antibody (1X697) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-Dectin-1 Antibody (1X697) is a Rabbit antibody targeting Dectin-1. Anti-Dectin-1 Antibody (1X697) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
1X697
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Dectin-1 / CLEC7A (rM Dectin-1 / CLEC7A; TMPY-01387; NP_064392.2; Phe69-Leu244).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection. In addition, dectin-1 is involved in the adaptive immune response as well as autoimmune diseases and immune tolerance. Dectin-1 can recognize and respond to live fungal pathogens and is being increasingly appreciated as having a key role in the innate responses to these pathogens. In addition to its exogenous ligands, Dectin-1 can recognize an unidentified endogenous ligand on T cells and may act as a co-stimulatory molecule. Recent studies have highlighted the importance of Dectin-1 in anti-fungal immunity, in both mice and humans, and have suggested a possible involvement of this receptor in the control of mycobacterial infections.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Dectin-1 / CLEC7A Protein (TMPY-01387)
Antigen Species
Mouse
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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