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Anti-DCLK1 Antibody (1W822) is a Mouse antibody targeting DCLK1. Anti-DCLK1 Antibody (1W822) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-DCLK1 Antibody (1W822) is a Mouse antibody targeting DCLK1. Anti-DCLK1 Antibody (1W822) can be used in ELISA. |
Alias | doublecortin-like kinase 1, DCLK, DCDC3A, DCAMKL1, CLICK1, CL1 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1W822 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DCAMKL1 / DCLK1 (rh DCLK1; TMPY-04404; O15075-1; Met1-Val705). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Its microtubule-polymerizing activity is independent of its protein kinase activity. DCAMKL1 may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It may also participate in functions of the mature nervous system. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human DCAMKL1 / DCLK1 protein (TMPY-04404) |
Antigen Species | Human |
Biology Area | Calcium-binding Proteins and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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