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Bedinvetmab

😃Good
Catalog No. T76813Cas No. 2171034-69-6
Alias ZTS-00508841, ZTS00508841

Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) engineered to target nerve growth factor (NGF). Bedinvetmab prevents NGF from binding its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR). Bedinvetmab is primarily utilized in osteoarthritis research, where it is studied for its ability to manage pain in canine models.

Bedinvetmab

Bedinvetmab

😃Good
Purity: 95%
Catalog No. T76813Alias ZTS-00508841, ZTS00508841Cas No. 2171034-69-6
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) engineered to target nerve growth factor (NGF). Bedinvetmab prevents NGF from binding its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR). Bedinvetmab is primarily utilized in osteoarthritis research, where it is studied for its ability to manage pain in canine models.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$247-In Stock
5 mg$647-In Stock
10 mg$987-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.0% (SDS-PAGE); 96.5% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) engineered to target nerve growth factor (NGF). Bedinvetmab prevents NGF from binding its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR). Bedinvetmab is primarily utilized in osteoarthritis research, where it is studied for its ability to manage pain in canine models.
In vivo
Bedinvetmab (0.5-1 mg/kg, subcutaneous injection, every 28 days) can effectively alleviate pain associated with canine osteoarthritis [1]. Bedinvetmab (1 mg/kg, subcutaneous injection, monthly; 3-fold and 10-fold doses) demonstrated good tolerability when co-administered with Carprofen in normal laboratory beagle dogs [2].
SynonymsZTS-00508841, ZTS00508841
Reactivity
Human
Application
ELISA
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin＜ 1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Chemical Properties
Cas No.2171034-69-6
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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