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Deoxyartemisinin

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Catalog No. TN1568Cas No. 72826-63-2
Alias 2-deoxyartemisinin

Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria.

Deoxyartemisinin

Deoxyartemisinin

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Purity: 97.35%
Catalog No. TN1568Alias 2-deoxyartemisininCas No. 72826-63-2
Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$60In StockIn Stock
5 mg$142In StockIn Stock
10 mg$208In StockIn Stock
25 mg$356In StockIn Stock
50 mg$527-In Stock
1 mL x 10 mM (in DMSO)$530-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.35%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria.
In vitro
Biotransformation of artemisinin was investigated with two different cell lines of suspension cultures of Withania somnifera. Both cell lines exhibited potential to transform artemisinin into its nonperoxidic analogue, Deoxyartemisinin, by eliminating the peroxo bridge of artemisinin. The enzyme involved in the reaction is assumed to be artemisinin peroxidase, and its activity in extracts of W. somnifera leaves was detected[1]
Synonyms2-deoxyartemisinin
Chemical Properties
Molecular Weight266.33
FormulaC15H22O4
Cas No.72826-63-2
SmilesC[C@@H]1[C@]2([C@]34[C@@](O[C@](C)(O3)CC[C@]4([C@H](C)CC2)[H])(OC1=O)[H])[H]
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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