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Anti-LOX-1 Antibody (2B645)
🥰Excellent
Catalog No. TMAY-03895
Anti-LOX-1 Antibody (2B645) is a Rabbit antibody targeting LOX-1. Anti-LOX-1 Antibody (2B645) can be used in ELISA.
Anti-LOX-1 Antibody (2B645)
Anti-LOX-1 Antibody (2B645)
🥰Excellent
Catalog No. TMAY-03895
Anti-LOX-1 Antibody (2B645) is a Rabbit antibody targeting LOX-1. Anti-LOX-1 Antibody (2B645) can be used in ELISA.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-LOX-1 Antibody (2B645) is a Rabbit antibody targeting LOX-1. Anti-LOX-1 Antibody (2B645) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2B645 |
| Reactivity | Cynomolgus |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus OLR1 / LOX1 (TMPY-03351; G7PJT2; Ser61-Gln273). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is induced by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes, and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Cynomolgus OLR1 / LOX1 Protein (TMPY-03351) |
| Antigen Species | Cynomolgus |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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