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STING Agonist 12b

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Catalog No. T38159Cas No. 2411100-70-2

STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

STING Agonist 12b

STING Agonist 12b

😃Good
Catalog No. T38159Cas No. 2411100-70-2
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
Pack SizePriceAvailabilityQuantity
500 μg$17835 days
1 mg$31635 days
5 mg$1,29035 days
10 mg$2,39035 days
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Product Introduction

Bioactivity
Description
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
Chemical Properties
Molecular Weight253.3
FormulaC16H15NO2
Cas No.2411100-70-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1 mg/mL (3.95 mM), Sonication is recommended.
DMF: 1 mg/mL (3.95 mM), Sonication is recommended.
Solution Preparation Table
DMSO/DMF
1mg5mg10mg50mg
1 mM3.9479 mL19.7394 mL39.4789 mL197.3944 mL

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STING Agonist 12b
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