Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 123.00 | |
1 mg | 35 days | $ 218.00 | |
5 mg | 35 days | $ 890.00 | |
10 mg | 35 days | $ 1,660.00 |
Description | STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells. |
Molecular Weight | 253.3 |
Formula | C16H15NO2 |
CAS No. | 2411100-70-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1 mg/mL
DMF: 1 mg/mL
You can also refer to dose conversion for different animals. More
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STING Agonist 12b 2411100-70-2 inhibitor inhibit