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1-Dodecanol

Name: 1-Dodecanol
Brand: TargetMol
SKU: T9514
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9514Cas No. 112-53-8

1-Dodecanol, an endogenous metabolite and saturated fatty alcohol derived from coconut oil fatty acids, is characterized by a floral odor. It is utilized in detergents, Lepidopteran pheromone/sex attractant, lubricating oils, pesticides, and pharmaceuticals.

1-Dodecanol

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Purity: 99.88%

Catalog No. T9514Cas No. 112-53-8

Pack Size	Price	USA Warehouse	Global Warehouse
5 g	$37	-	In Stock
10 g	$52	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.88%

Appearance:Solid

Color:White

Resource Download

COA GC HNMR

Product Introduction

1-Dodecanol AI Summary

1-Dodecanol exhibits diverse bioactivities, making it a potential candidate for various therapeutic applications. It demonstrates significant antimicrobial properties, including antibacterial activity against Staphylococcus aureus (MIC: 6.25 µg/mL) and methicillin-resistant Staphylococcus aureus ATCC 43300 (with potentiation of oxacillin at 32 µg/mL and an MIC > 256.0 µg/mL). It also shows notable effects against Propionibacterium acnes, with an MIC of 3.13 µg/mL and an MBC of 6.25 µg/mL. Additionally, 1-Dodecanol exhibits antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 at an MIC of 5.0 µg/mL and antifungal activity against Saccharomyces cerevisiae ATCC 7754 with an MFC greater than 1600.0 µg/mL. The compound also shows nematicidal activity against Bursaphelenchus xylophilus at 0.5 mg/mL, with a nematode mortality rate of 3.1% over 48 hours. Other notable bioactivities include inhibition of mouse brain synaptosomal Lysophosphatidylcholine acyltransferase, antihemolytic potency against hypotonic lysis-induced erythrocytes, and agonist activity at TRPA1 at 1000 µM with a 12.0% activity level relative to AITC..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	186.33
Formula	C₁₂H₂₆O
Cas No.	112-53-8
Smiles	CCCCCCCCCCCCO
Relative Density.	0.833 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (241.51 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.73 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3668 mL	26.8341 mL	53.6682 mL	268.3411 mL
5 mM	1.0734 mL	5.3668 mL	10.7336 mL	53.6682 mL
10 mM	0.5367 mL	2.6834 mL	5.3668 mL	26.8341 mL
20 mM	0.2683 mL	1.3417 mL	2.6834 mL	13.4171 mL
50 mM	0.1073 mL	0.5367 mL	1.0734 mL	5.3668 mL
100 mM	0.0537 mL	0.2683 mL	0.5367 mL	2.6834 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc