Shopping Cart
Remove All
Your shopping cart is currently empty
Avicularin
Copy Product Info
😃Good
Catalog No. T6S0117Cas No. 572-30-5
Alias Fenicularin
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX-2, and PPAR-γ. In LPS-stimulated RAW 264.7 macrophages, it exerts anti-inflammatory activity by inhibiting the ERK signaling pathway.
Avicularin
Copy Product Info😃Good
Purity: 99.94%
Catalog No. T6S0117Alias FenicularinCas No. 572-30-5
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX-2, and PPAR-γ. In LPS-stimulated RAW 264.7 macrophages, it exerts anti-inflammatory activity by inhibiting the ERK signaling pathway.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $53 | In Stock | In Stock | |
| 5 mg | $98 | In Stock | In Stock | |
| 10 mg | $163 | In Stock | In Stock | |
| 25 mg | $297 | In Stock | In Stock | |
| 50 mg | $439 | In Stock | In Stock | |
| 100 mg | $648 | - | In Stock | |
| 200 mg | $925 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $113 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.94%
Color:White to Yellow
Contact us for more batch information
Product Introduction
Avicularin AI Summary
Avicularin exhibits a multifaceted profile of bioactivity across various biological systems. It inhibits cow milk xanthine oxidase activity by 30.8% at a concentration of 50 µg/mL and demonstrates notable procoagulant inhibition in human monocytes by counteracting IL1-induced tissue factor expression at 10 µM after 18 hours, resulting in 0.0 microunits of tissue factor per 10^5 cells. The compound is also effective against algae, showing antialgal activity with IC50 values of 180,000.0 nM for Microcystis aeruginosa NIES 44 and 28,000.0 nM for Anabaena flos-aquae NIES 73. Additionally, Avicularin inhibits human recombinant aldose reductase (IC50: 19050.0 nM) and chicken liver Fatty Acid Synthase (FASN) (IC50: 6150.0 nM). It also has antiviral activity against the Dengue virus, with an IC50 of 1700.0 nM, and shows cytotoxicity against human cancer cell lines SGC7901, A549, and HeLa with IC50 values >10.0 µg/mL. Furthermore, it has potent antioxidant activity, with DPPH and ABTS radical scavenging IC50 values of 16.13 µg/mL and 6.9 µg/mL, respectively, and exhibits increasing FRAP values at higher concentrations (25, 50, and 100 µg/mL). The compound displays antifungal properties with minimum inhibitory concentrations (MIC) of 2.0 µg/mL against Candida albicans and Aspergillus fumigatus ATTC 26934, and 8.0 µg/mL against Candida parapsilosis. Lastly, Avicularin acts as an agonist at TRPA1 channels with 41.0% activity at 1000 µM relative to AITC..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX-2, and PPAR-γ. In LPS-stimulated RAW 264.7 macrophages, it exerts anti-inflammatory activity by inhibiting the ERK signaling pathway. |
| Synonyms | Fenicularin |
| Molecular Weight | 434.35 |
| Formula | C20H18O11 |
| Cas No. | 572-30-5 |
| Smiles | OC[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)[C@H](O)[C@H]1O |
| Relative Density. | 1.86 g/cm3 (Predicted) |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 1.15 mg/mL (2.65 mM), Sonication is recommended. DMSO: 120 mg/mL (276.27 mM)  | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
| |||||||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
RAW 264.7PPARPeroxisome proliferator-activated receptorsoxidative stressosteoarthritisNuclear factor-κBNuclear factor-kappaBNF-κBmacrophagesLPSlipidsInhibitorinhibitinflammationHCCGLUTGlucose transporterExtracellular signal regulated kinasesERKECMCyclooxygenaseCOXAvicularinApoptosisAlzheimer's diseaseadipocytes3T3-L1
Preview
Related Tags: buy Avicularin | purchase Avicularin | Avicularin cost | order Avicularin | Avicularin chemical structure | Avicularin formula | Avicularin molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.