Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Zn(BQTC) is a potent inhibitor of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage that disrupts mitochondrial and nuclear functions sequentially. It facilitates apoptotic signaling pathways triggered by DNA damage and exhibits selective antiproliferative effects on A549R cells, rendering it useful for anticancer research [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,670.00 | |
50 mg | 8-10 weeks | $ 2,180.00 | |
100 mg | 8-10 weeks | $ 2,800.00 |
Description | Zn(BQTC) is a potent inhibitor of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage that disrupts mitochondrial and nuclear functions sequentially. It facilitates apoptotic signaling pathways triggered by DNA damage and exhibits selective antiproliferative effects on A549R cells, rendering it useful for anticancer research [1]. |
In vitro | Zn(BQTC) (0-100 μM; 6 hours) demonstrates potent and selective antiproliferative effects on A549R cells, with an IC50 value of 10 nM [1]. |
Molecular Weight | 650.92 |
Formula | C30H36Cl2N5O3Zn |
CAS No. | 2785342-54-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Zn(BQTC) 2785342-54-1 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis inhibitor inhibit