Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1]. |
Targets&IC50 | SIRT5:0.21 μM |
In vitro | SIRT5 inhibitor 5 (compound 47) (0-10 µM) exhibits consistent inhibitory activity across varying concentrations of NAD+ (50, 100, 200, 400, 800 µM) and shows reduced inhibitory potency with increasing concentrations of Ac-K(Suc)-AMC (10, 30, 90, 270 µM) [1]. |
Molecular Weight | 423.87 |
Formula | C21H14ClN3O3S |
CAS No. | 2883730-60-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SIRT5 inhibitor 5 2883730-60-5 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin inhibitor inhibit