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Sonoflora 1

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Catalog No. T34686Cas No. 1609250-37-4
Alias Sonoflora-1, Sonoflora1, SF-1, SF1, SF 1

Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.

Sonoflora 1

Sonoflora 1

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Catalog No. T34686Alias Sonoflora-1, Sonoflora1, SF-1, SF1, SF 1Cas No. 1609250-37-4
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.
SynonymsSonoflora-1, Sonoflora1, SF-1, SF1, SF 1
Chemical Properties
Molecular Weight927.441
FormulaC38H39N6Na3O10Sn
Cas No.1609250-37-4
Smiles[Na+].[Na+].[Na+].CCC1=C(C)C2=[N]3C1=CC1=C(C)C(C([O-])=O)=C4[N-]1[Sn+4]31([OH-])([OH-])[N-]3C(=CC5=[N]1C(C(CCC([O-])=O)C5C)=C4CC(=O)NCC(=O)NCC([O-])=O)C(C)=C(C=C)C3=C2 |c:2,5,10,16,25,27,39,60,t:8,55,^1:9,20,24,28|jcExt:v:22:2,23:2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

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