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5-HT7 agonist 1

Name: 5-HT7 agonist 1
Brand: TargetMol
SKU: T10170
Price: 117 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10170Cas No. 334974-31-1

Alias 4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole, 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole, 4-[4-(2-chlorobenzyl)piperazino]-1H-indole

5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM). 5-HT7 agonist 1 can be used in studies about CNS disorders.

5-HT7 agonist 1

🥰Excellent

Purity: 98.61%

Catalog No. T10170Alias 4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole, 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole, 4-[4-(2-chlorobenzyl)piperazino]-1H-indoleCas No. 334974-31-1

5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM). 5-HT7 agonist 1 can be used in studies about CNS disorders.

Pack Size	Price	Availability
1 mg	$117	In Stock
2 mg	$175	In Stock
5 mg	$268	In Stock
10 mg	$395	In Stock
25 mg	$592	In Stock
50 mg	$828	In Stock
100 mg	$1,130	In Stock
1 mL x 10 mM (in DMSO)	$268	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:98.61%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM). 5-HT7 agonist 1 can be used in studies about CNS disorders.
Synonyms	4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole, 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole, 4-[4-(2-chlorobenzyl)piperazino]-1H-indole

Chemical Properties

Molecular Weight	325.84
Formula	C₁₉H₂₀ClN₃
Cas No.	334974-31-1
Smiles	C(N1CCN(C2=C3C(=CC=C2)NC=C3)CC1)C4=C(Cl)C=CC=C4
Relative Density.	1.275 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (138.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0690 mL	15.3450 mL	30.6899 mL	153.4495 mL
5 mM	0.6138 mL	3.0690 mL	6.1380 mL	30.6899 mL
10 mM	0.3069 mL	1.5345 mL	3.0690 mL	15.3450 mL
20 mM	0.1534 mL	0.7672 mL	1.5345 mL	7.6725 mL
50 mM	0.0614 mL	0.3069 mL	0.6138 mL	3.0690 mL
100 mM	0.0307 mL	0.1534 mL	0.3069 mL	1.5345 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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