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Tamtuvetmab

(Synonyms: AT-005, AT005) Copy Product Info
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Synonyms: AT-005, AT005

Catalog No. T81046 Copy Product Info
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Tamtuvetmab (AT-005), a caninised version of blontuvetmab targeting CD52, enhances progression-free survival (PFS) and demonstrates in vivo efficacy for treating naïve T-cell lymphoma (LSA) in dogs. The compound has received veterinary approval [1] [2].
Tamtuvetmab
Cas No. 1608122-71-9
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$328-In Stock
5 mg$993-In Stock
10 mg$1,570-In Stock
25 mg$2,890-In Stock
50 mg$4,650-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.0% (SDS-PAGE); 98.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tamtuvetmab (AT-005), a caninised version of blontuvetmab targeting CD52, enhances progression-free survival (PFS) and demonstrates in vivo efficacy for treating naïve T-cell lymphoma (LSA) in dogs. The compound has received veterinary approval [1] [2].
In vivo
Tamtuvetmab, administered intravenously at a concentration of 5 mg/mL and volumes ranging from 7.5 to 30 mL over 15 to 30 minutes, demonstrates in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). However, it is associated with adverse effects including vomiting, weight loss, diarrhea, lethargy, reduced appetite, and anorexia [1].
SynonymsAT-005, AT005
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetCD25
Chemical Properties
Cas No.1608122-71-9
Antibody Information
IsotypeCanine lgG lambda
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Tamtuvetmab in vivo