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Anti-C1 inhibitor Antibody (7X93)
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Catalog No. TMAY-01438
Alias serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Anti-C1 inhibitor Antibody (7X93) is a Rabbit antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (7X93) can be used in WB,ELISA,ELISA(Det),IP.
Anti-C1 inhibitor Antibody (7X93)
Anti-C1 inhibitor Antibody (7X93)
😃Good
Catalog No. TMAY-01438Alias serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Anti-C1 inhibitor Antibody (7X93) is a Rabbit antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (7X93) can be used in WB,ELISA,ELISA(Det),IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-C1 inhibitor Antibody (7X93) is a Rabbit antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody (7X93) can be used in WB,ELISA,ELISA(Det),IP. |
| Alias | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7X93 |
| Reactivity | Human |
| Verified Activity | 1. SERPING1 was immunoprecipitated using: -Lane A:0.5 mg HepG2 Whole Cell Lysate. -2 µL anti-SERPING1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-SERPING1 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 55 kDa. -Observed band size: 100 kDa. 2. Anti-SerpinG1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:55 kDa. -Observed band size:71 kDa |
| Application | WB,ELISA,ELISA(Det),IP |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 0.5-2 μL/mg of lysate; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinG1 (rh SerpinG1; TMPY-01183; NP_000053.2; Met 1-Ala 500). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human SerpinG1 protein (TMPY-01183) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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