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Anti-M-CSF/CSF1 Antibody (1B24) (Synonyms: M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage))

Name: Anti-M-CSF/CSF1 Antibody (1B24)
Brand: TargetMol
SKU: TMAY-02059
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02059 Copy Product Info

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Anti-M-CSF/CSF1 Antibody (1B24) is a Mouse antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (1B24) can be used in ELISA.

Anti-M-CSF/CSF1 Antibody (1B24)

Copy Product Info

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Catalog No. TMAY-02059

Synonyms M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage)

Anti-M-CSF/CSF1 Antibody (1B24) is a Mouse antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (1B24) can be used in ELISA.

Anti-M-CSF/CSF1 Antibody
(1B24)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-M-CSF/CSF1 Antibody (1B24) is a Mouse antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (1B24) can be used in ELISA.
Synonyms	M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage)
Ig Type	Mouse IgG1
Clone	1B24
Reactivity	Human
Specificity	Human M-CSF/CSF1
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human M-CSF/CSF-1 (rh M-CSF/CSF-1; P09603-1Met1-Asn190). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human M-CSF/CSF-1 Protein
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

macrophageCSF1CSF 1colony stimulating factor 1

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