Shopping Cart

Your shopping cart is currently empty

Sanguisorbigenin

Name: Sanguisorbigenin
Brand: TargetMol
SKU: TN4943
Price: 163 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. TN4943Cas No. 6812-98-2

Alias Ursa-12,19-dien-28-oic acid, Tomentosolic acid, 3β-Hydroxyurs-12,19-dien-28-oic acid, 19-Dehydroursolic acid

Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).

Sanguisorbigenin

Copy Product Info

🥰Excellent

Purity: 99.56%

Catalog No. TN4943Alias Ursa-12,19-dien-28-oic acid, Tomentosolic acid, 3β-Hydroxyurs-12,19-dien-28-oic acid, 19-Dehydroursolic acidCas No. 6812-98-2

Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$163	In Stock	In Stock
5 mg	$398	In Stock	In Stock
10 mg	$596	In Stock	In Stock
25 mg	$882	In Stock	In Stock
50 mg	$1,190	In Stock	In Stock
100 mg	$1,600	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$458	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.56%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).
In vitro	Treatment of Sanguisorbigenin with sub-MIC concentrations (1.56-6.25 μg/mL) significantly inhibited the expression of blaR1, mecA, and blaZ in MRSA dose-dependently. The gene expression of mecA is remarkably reduced after the treatment of Sanguisorbigenin. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decreasing PBP2a expression[1].
Synonyms	Ursa-12,19-dien-28-oic acid, Tomentosolic acid, 3β-Hydroxyurs-12,19-dien-28-oic acid, 19-Dehydroursolic acid

Chemical Properties

Molecular Weight	454.69
Formula	C₃₀H₄₆O₃
Cas No.	6812-98-2
Smiles	[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])C(C)=C(C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
Relative Density.	1.11 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (131.96 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 1.67 mg/mL (3.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1993 mL	10.9965 mL	21.9930 mL	109.9650 mL
5 mM	0.4399 mL	2.1993 mL	4.3986 mL	21.9930 mL
10 mM	0.2199 mL	1.0997 mL	2.1993 mL	10.9965 mL
20 mM	0.1100 mL	0.5498 mL	1.0997 mL	5.4983 mL
50 mM	0.0440 mL	0.2199 mL	0.4399 mL	2.1993 mL
100 mM	0.0220 mL	0.1100 mL	0.2199 mL	1.0997 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc