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Fostemsavir

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Catalog No. T3523Cas No. 864953-29-7
Alias BMS-663068

Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.

Fostemsavir

Fostemsavir

😃Good
Purity: 98.95%
Catalog No. T3523Alias BMS-663068Cas No. 864953-29-7
Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$54In StockIn Stock
5 mg$123In StockIn Stock
10 mg$179In StockIn Stock
25 mg$297In StockIn Stock
50 mg$455In StockIn Stock
100 mg$655-In Stock
200 mg$918-In Stock
1 mL x 10 mM (in DMSO)$158In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.95%
Color:White
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Product Introduction

Bioactivity
Description
Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
SynonymsBMS-663068
Chemical Properties
Molecular Weight583.49
FormulaC25H26N7O8P
Cas No.864953-29-7
SmilesC(OP(=O)(O)O)N1C=2C(C(C(C(=O)N3CCN(C(=O)C4=CC=CC=C4)CC3)=O)=C1)=C(OC)C=NC2N5N=C(C)N=C5
Relative Density.1.60 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 255 mg/mL (437.03 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7138 mL8.5691 mL17.1383 mL85.6913 mL
5 mM0.3428 mL1.7138 mL3.4277 mL17.1383 mL
10 mM0.1714 mL0.8569 mL1.7138 mL8.5691 mL
20 mM0.0857 mL0.4285 mL0.8569 mL4.2846 mL
50 mM0.0343 mL0.1714 mL0.3428 mL1.7138 mL
100 mM0.0171 mL0.0857 mL0.1714 mL0.8569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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