keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 35 days | $ 1,140.00 |
Description | Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. |
In vitro | In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans. |
Molecular Weight | 5929.4 |
Formula | C269H381N67O82S2CF3COOH |
CAS No. | 136461-80-8 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Formic Acid: 1 mg/mL
You can also refer to dose conversion for different animals. More
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Osteocalcin (1-49) (human) (trifluoroacetate salt) 136461-80-8 Osteocalcin (1 49) (human) (trifluoroacetate salt) Osteocalcin (149) (human) (trifluoroacetate salt) Osteocalcin inhibitor inhibit