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Bax activator-1 (compound 106) is a Bax activator that induces Bax-dependent tumor cell apoptosis[1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks | 6-8 weeks |
| Description | Bax activator-1 (compound 106) is a Bax activator that induces Bax-dependent tumor cell apoptosis[1]. |
| In vitro | Bax activator-1 (20-80 μM; 48 hours) induces Bax-dependent tumor cell apoptosis in a dose-dependent manner [1]. |
| In vivo | Bax activator-1 (40 mg/kg; administered i.p. daily for 13 days) inhibits lung tumor growth in C57BL/6 female mice[1]. |
| Molecular Weight | 488.62 |
| Formula | C29H36N4O3 |
| Cas No. | 1638526-94-9 |
| Smiles | COc1cccc(Cn2nc(C(=O)N3CCC[C@@H](O)C3)c3CN(Cc4ccc(C)c(C)c4)CCc23)c1 |
| Relative Density. | 1.24 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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