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Anti-UBE2D1 Antibody (3N219) (Synonyms: ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(...)
Catalog No. TMAY-01865 Copy Product Info
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Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM.
Anti-UBE2D1 Antibody (3N219)
Copy Product Info🥰Excellent
Catalog No. TMAY-01865
Synonyms ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1
Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM.
Anti-UBE2D1 Antibody
(3N219)
(3N219)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM. |
| Synonyms | ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1 |
| Ig Type | Mouse IgG2a |
| Clone | 3N219 |
| Reactivity | Human |
| Specificity | Human UbcH5/UBE2D1 |
| Verified Activity | Flow cytometric analysis of Human UBE2D1 expression on A431 cells. Cells were stained with purified anti-Human UBE2D1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human UBE2D1 Protein (TMPY-02426) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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