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Anti-UBE2D1 Antibody (3N219)

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Catalog No. TMAY-01865
Alias ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1

Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM.

Anti-UBE2D1 Antibody (3N219)

Anti-UBE2D1 Antibody (3N219)

😃Good
Catalog No. TMAY-01865Alias ubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1
Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM.
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100 μL$199 7-10 days
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Instruction Manual of Detection Antibody
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Mouse Monoclonal

Application: FCM

Reactivity: Human
Aliasubiquitin-conjugating enzyme E2D 1, UBCH5A, UBCH5, UBC4/5, SFT, E2(17)KB1
Ig Type
Mouse IgG2a
Clone
3N219
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human UBE2D1 expression on A431 cells. Cells were stained with purified anti-Human UBE2D1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundUbiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human UBE2D1 Protein (TMPY-02426)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

UBCH-5UBCH 5
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