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Anti-FLRT1 Antibody (4M341) (Synonyms: SPG68, fibronectin leucine rich transmembrane protein 1)
Catalog No. TMAY-01853 Copy Product Info
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Anti-FLRT1 Antibody (4M341) is a Mouse antibody targeting FLRT1. Anti-FLRT1 Antibody (4M341) can be used in ELISA.
Anti-FLRT1 Antibody (4M341)
Copy Product Info🥰Excellent
Catalog No. TMAY-01853
Synonyms SPG68, fibronectin leucine rich transmembrane protein 1
Anti-FLRT1 Antibody (4M341) is a Mouse antibody targeting FLRT1. Anti-FLRT1 Antibody (4M341) can be used in ELISA.
Anti-FLRT1 Antibody
(4M341)
(4M341)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-FLRT1 Antibody (4M341) is a Mouse antibody targeting FLRT1. Anti-FLRT1 Antibody (4M341) can be used in ELISA. |
| Synonyms | SPG68, fibronectin leucine rich transmembrane protein 1 |
| Ig Type | Mouse IgG1 |
| Clone | 4M341 |
| Reactivity | Human |
| Specificity | Human FLRT1 No cross-reactivity in ELISA with Human FLRT2 Human FLRT3 Human cell lysate (293 cell line) |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FLRT1 (rh FLRT1; TMPY-02032; Q9NZU1-1; Met 1-Pro 524). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1 is expressed in kidney and brain, which is a target for tyrosine phosphorylation mediated by FGFR1 and implicates a non-receptor Src family kinase (SFK). All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. The phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR. This is consistent with an 'in vivo' role for FLRT1 regulation of FGF signalling via SFKs. Furthermore, the phosphorylation-dependent futile cycle mechanism controlling FGFR1 signalling is concurrently crucial for regulation of FLRT1-mediated neurite outgrowth. FLRT1, FLRT2 and FLRT3 are members of the fibronectin leucine rich transmembrane protein (FLRT) family. They may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. FLRT3 shares 55% amino acid sequence identity with FLRT1. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human FLRT1 protein (TMPY-02032) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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