Powder: -20°C for 3 years | In solvent: -80°C for 1 year
cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1].
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Description | cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1]. |
Molecular Weight | 377.35 |
Formula | C18H19NO8 |
CAS No. | 858770-07-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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cGAS-IN-1 858770-07-7 inhibitor inhibit