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Vobramitamab

😃Good
Catalog No. T77905Cas No. 2490556-50-6
Alias AEX-4089, AEX4089

Vobramitamab (AEX-4089) is a humanized monoclonal antibody (mAb) targeting the B7-H3 antigen (CD276) which is conjugated to the prodrug seco-duocarmycin hydroxybenzamide azaindole (seco-DUBA) through a enzymatically cleavable peptide-based linker, thereby creating the investigational antibody-drug conjugate (ADC) known as MGC018.

Vobramitamab

Vobramitamab

😃Good
Purity: 95%
Catalog No. T77905Alias AEX-4089, AEX4089Cas No. 2490556-50-6
Vobramitamab (AEX-4089) is a humanized monoclonal antibody (mAb) targeting the B7-H3 antigen (CD276) which is conjugated to the prodrug seco-duocarmycin hydroxybenzamide azaindole (seco-DUBA) through a enzymatically cleavable peptide-based linker, thereby creating the investigational antibody-drug conjugate (ADC) known as MGC018.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$332-In Stock
5 mg$929-In Stock
10 mg$1,490-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.1% (SDS-PAGE); 97.1% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Vobramitamab (AEX-4089) is a humanized monoclonal antibody (mAb) targeting the B7-H3 antigen (CD276) which is conjugated to the prodrug seco-duocarmycin hydroxybenzamide azaindole (seco-DUBA) through a enzymatically cleavable peptide-based linker, thereby creating the investigational antibody-drug conjugate (ADC) known as MGC018.
Targets&IC50
NB cell lines:17.8-364 ng/mL (IC50)
SynonymsAEX-4089, AEX4089
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetB7-H3/CD276
Chemical Properties
Molecular Weight144.64 kDa
Cas No.2490556-50-6
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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