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Anti-LRG1 Antibody (4R448) is a Rabbit antibody targeting LRG1. Anti-LRG1 Antibody (4R448) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-LRG1 Antibody (4R448) is a Rabbit antibody targeting LRG1. Anti-LRG1 Antibody (4R448) can be used in ELISA. |
Alias | LRG, leucine-rich α-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1, HMFT1766 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4R448 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human LRG1 (rh LRG1; TMPY-03966; AAH34389.1; Met1-Gln347). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human LRG1 Protein (TMPY-03966) |
Antigen Species | Human |
Biology Area | Cardiac Stem Cell Markers |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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