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RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR (cystic fibrosis transmembrane conductance regulator with a deletion at position 508 of phenylalanine) and regulate ATG4B and paxillin, making it useful for studying cystic fibrosis (CF).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $78 | In Stock | |
5 mg | $189 | In Stock | |
10 mg | $328 | In Stock | |
25 mg | $689 | In Stock | |
50 mg | $1,180 | In Stock | |
100 mg | $1,980 | In Stock | |
200 mg | $2,680 | In Stock | |
1 mL x 10 mM (in DMSO) | $198 | In Stock |
Description | RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR (cystic fibrosis transmembrane conductance regulator with a deletion at position 508 of phenylalanine) and regulate ATG4B and paxillin, making it useful for studying cystic fibrosis (CF). |
Molecular Weight | 384.5 |
Formula | C23H20N4S |
Cas No. | 324579-65-9 |
Smiles | N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C1C)CC=4C=CC=CC4 |
Color | Yellow |
Appearance | Solid |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (208.06 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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