Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Anti-RIZ1 Antibody (7G445) (Synonyms: RIZ2, RIZ1, RIZ, PR domain containing 2, with ZNF domain, MTB-ZF, KMT...)

Name: Anti-RIZ1 Antibody (7G445)
Brand: TargetMol
SKU: TMAY-01762
Rating: 4.5 (1 reviews)

Catalog No. TMAY-01762 Copy Product Info

🥰Excellent

Anti-RIZ1 Antibody (7G445) is a Mouse antibody targeting RIZ1. Anti-RIZ1 Antibody (7G445) can be used in ELISA.

Anti-RIZ1 Antibody (7G445)

Copy Product Info

🥰Excellent

Catalog No. TMAY-01762

Synonyms RIZ2, RIZ1, RIZ, PR domain containing 2, with ZNF domain, MTB-ZF, KMT8, HUMHOXY1

Anti-RIZ1 Antibody (7G445) is a Mouse antibody targeting RIZ1. Anti-RIZ1 Antibody (7G445) can be used in ELISA.

Anti-RIZ1 Antibody
(7G445)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-RIZ1 Antibody (7G445) is a Mouse antibody targeting RIZ1. Anti-RIZ1 Antibody (7G445) can be used in ELISA.
Synonyms	RIZ2, RIZ1, RIZ, PR domain containing 2, with ZNF domain, MTB-ZF, KMT8, HUMHOXY1
Ig Type	Mouse IgG1
Clone	7G445
Reactivity	Human
Specificity	Human RIZ1
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RIZ1 (rh RIZ1; TMPY-01265; NP_036363.2; Met1-Ala200). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	PR domain containing 2, with ZNF domain (PRDM2), also known as zinc finger protein RIZ, is a member of histone methyltransferase (HMT) class enzymes that methylate lysine residues of histones or proteins. HMTs contain a conserved catalytic core termed the SET domain, which shares sequence homology with an independently described sequence motif, the PR domain. PRDM2 contains 8 C2H2-type zinc fingers and a distinct SET domain, and is highly expressed in retinoblastoma cell lines and in brain tumors, as well as in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. PRDM2 is an S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3, and is identified as a tumor suppressor. It is reported that intact PR( SET) sequence is required for tumor suppression functions, mutations in the PR domain caused activity reduction in human cancers. Also, S-adenosylhomocysteine or methyl donor deficiency inhibits RIZ1 and other H3 lysine 9 methylation activities. PRDM2 may also function as a DNA-binding transcription factor. It binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and acts as a transcriptional activator. Besides, PRDM2 (RIZ) can bind to the retinoblastoma protein (RB) and also Interacts with GATA3.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human RIZ1 Protein (TMPY-01265)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

Calculator

Dilution Calculator
Reconstitution Calculator

Keywords

RIZ-2RIZ-1RIZ 2RIZ 1KMT-8KMT 8HUMHOXY-1HUMHOXY 1

Related Tags: buy Anti-RIZ1 Antibody (7G445) | purchase Anti-RIZ1 Antibody (7G445) | Anti-RIZ1 Antibody (7G445) cost | order Anti-RIZ1 Antibody (7G445)