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CARM1-IN-1

Name: CARM1-IN-1
Brand: TargetMol
SKU: T10682L
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10682LCas No. 1020399-49-8

Alias CARM1-IN-7G

CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.

CARM1-IN-1

🥰Excellent

Purity: 98.24%

Catalog No. T10682LAlias CARM1-IN-7GCas No. 1020399-49-8

CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.

Pack Size	Price	Availability
1 mg	$31	In Stock
5 mg	$81	In Stock
10 mg	$129	In Stock
25 mg	$263	In Stock
50 mg	$428	In Stock
100 mg	$666	In Stock
200 mg	$929	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:98.24%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.
In vitro	In human LNCaP cells, CARM1-IN-1 significantly reduces the PSA promoter activity in a dose-dependent manner[1].
Synonyms	CARM1-IN-7G

Chemical Properties

Molecular Weight	555.26
Formula	C₂₆H₂₁Br₂NO₃
Cas No.	1020399-49-8
Smiles	Oc1ccc(\C=C2/CN(Cc3ccccc3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br
Relative Density.	1.647 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8010 mL	9.0048 mL	18.0096 mL	90.0479 mL
5 mM	0.3602 mL	1.8010 mL	3.6019 mL	18.0096 mL
10 mM	0.1801 mL	0.9005 mL	1.8010 mL	9.0048 mL
20 mM	0.0900 mL	0.4502 mL	0.9005 mL	4.5024 mL
50 mM	0.0360 mL	0.1801 mL	0.3602 mL	1.8010 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc