Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. It further induces apoptosis and cell cycle arrest. When used alongside other anticancer agents like statins, Dalotuzumab's antitumor activity is significantly enhanced both in vitro and in vivo [1] [2] [3].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry |
Description | Dalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. It further induces apoptosis and cell cycle arrest. When used alongside other anticancer agents like statins, Dalotuzumab's antitumor activity is significantly enhanced both in vitro and in vivo [1] [2] [3]. |
Molecular Weight | 146.4 (kDa) |
CAS No. | 1005389-60-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dalotuzumab 1005389-60-5 inhibitor inhibit