inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10876	CPA inhibitor	Carboxypeptidase inhibitor	Carboxypeptidase
	CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.		Carboxypeptidase
T1804	HPGDS inhibitor 1	HPGDS-inhibitor-1	PGE Synthase
	HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM.		PGE Synthase
T8766	GOT1 inhibitor-1	GOT1 inhibitor 2c	Others
	GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.		Others
T5451	Eph inhibitor 2	Ehp-inhibitor-1	Ephrin Receptor
	Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.		Ephrin Receptor
T38683	SCD1 inhibitor-3	SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a	Dehydrogenase
	SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesit...		Dehydrogenase
T4338	USP7/USP47 inhibitor	USP7/47 inhibitor-1	DUB
	USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively.		DUB
T3042	JAK2 Inhibitor V	JAK2 Inhibitor V Z3,Z3	JAK
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.		JAK
T2074	Raf inhibitor 1	B-Raf inhibitor 1	Raf
	B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.		Raf
T6335	Tie2 kinase inhibitor 1	Tie2 kinase inhibitor	Tie-2
	Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.		Tie-2
T3593	Src Inhibitor 1	Src Kinase Inhibitor 1,Src-l1	Src
	Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.		Src
T5817	PKC-theta inhibitor hcl	PKC-theta inhibitor	PKC
	PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).		PKC
T2350	MALT1 inhibitor MI-2	MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)	MALT
	MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.		MALT
T5524	Aurora kinase inhibitor-3	Aurora Kinase Inhibitor III	Aurora Kinase
	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.		Aurora Kinase
T67767	HIF-1 inhibitor-4	HIF-1 inhibitor-4	HIF
	HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.		HIF
T3189	B7/CD28 interaction inhibitor 1	CTLA-4 inhibitor	Others
	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.		Others
T24141	HIV-1 Inhibitor 18A	HIV-1 Inhibitor-18A	HIV Protease
	HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.		HIV Protease
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T10678	Carboxypeptidase G2 (CPG2) Inhibitor	CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor	Carboxypeptidase
	Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.		Carboxypeptidase
T4391	Syk Inhibitor II dihydrochloride	Syk Inhibitor II (hydrochloride)	Others , Tyrosine Kinases , Syk , PKC , BTK
	Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet fun...		Others , Tyrosine Kinases , Syk , PKC , BTK
T7541	PTP inhibitor 1	PTP Inhibitor II	Phosphatase
	PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM.		Phosphatase