Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 107.00 | |
25 mg | In stock | $ 259.00 | |
50 mg | In stock | $ 467.00 | |
100 mg | In stock | $ 685.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 118.00 |
Description | Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype. |
In vitro | The study investigates the impact of selectively inhibiting Akt in proliferating cells that express Trop-2. In cells expressing Trop-2, Akt inhibition, whether achieved through silencing or specific drugs, significantly reduces cell proliferation in a dose-dependent manner.[1] |
In vivo | When Trop-2-expressing tumors are subcutaneously injected into animal models, they exhibit a remarkable reduction in growth upon treatment with specific drugs targeting Akt activity. This underscores the central functional role of Akt in mediating the Trop-2-dependent growth stimulus.[1] |
Synonyms | Rivanicline 2HCl(15585-43-0 Free base) |
Molecular Weight | 235.15 |
Formula | C10H16Cl2N2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (212.63 mM)
You can also refer to dose conversion for different animals. More
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Rivanicline 2HCl Neuroscience AChR Rivanicline 2HCl(15585-43-0 Free base) Rivanicline inhibitor inhibit