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Cletoquine
🥰Excellent
Catalog No. T10835Cas No. 4298-15-1
Alias Desethylhydroxychloroquine
Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
Cletoquine
🥰Excellent
Purity: 99.98%
Catalog No. T10835Alias DesethylhydroxychloroquineCas No. 4298-15-1
Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $291 | - | In Stock | |
| 5 mg | $715 | - | In Stock | |
| 10 mg | $987 | - | In Stock | |
| 25 mg | $1,480 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $688 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment. |
| In vivo | Hydroxychloroquine is administered intravenously at a dosage of 5 mg/kg to BALB/c mice to assess the Cletoquine levels in blood and tissues. A tissue to blood concentration ratio (Kp) of ≥1 signifies Cletoquine's accumulation in tissues. The observed descending order of the Cletoquine Kp ratios across various tissues is liver (114.3), kidney (24.4), spleen (19.3), lungs (16.5), and heart (5.5). |
| Synonyms | Desethylhydroxychloroquine |
| Molecular Weight | 307.82 |
| Formula | C16H22ClN3O |
| Cas No. | 4298-15-1 |
| Smiles | N(C(CCCNCCO)C)C=1C2=C(N=CC1)C=C(Cl)C=C2 |
| Relative Density. | 1.212 g/cm3 |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from moisture,store under nitrogen | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (178.68 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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