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5'-Guanylic acid

Name: 5'-Guanylic acid
Brand: TargetMol
SKU: T19346
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: 5'-guanosine monophosphate, 5'-GMP) Copy Product Info

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Synonyms: 5'-guanosine monophosphate, 5'-GMP

Catalog No. T19346 Copy Product Info

Purity: 99.43%

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5'-Guanylic acid (5'-guanosine monophosphate) is implicated in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (APRT), and the 2-hydroxyglutric aciduria pathway.

Cas No. 85-32-5

Pack Size	Price	USA Stock	Global Stock	Quantity
100 mg	$30	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.43%

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	5'-Guanylic acid (5'-guanosine monophosphate) is implicated in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (APRT), and the 2-hydroxyglutric aciduria pathway.
Synonyms	5'-guanosine monophosphate, 5'-GMP

Chemical Properties

Molecular Weight	363.22
Formula	C₁₀H₁₄N₅O₈P
Cas No.	85-32-5
Smiles	O.Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
Relative Density.	2.47 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Keep away from direct sunlight,Store at low temperature,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: Insoluble

H2O: 50 mg/mL (137.66 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.7532 mL	13.7658 mL	27.5315 mL	137.6576 mL
5 mM	0.5506 mL	2.7532 mL	5.5063 mL	27.5315 mL
10 mM	0.2753 mL	1.3766 mL	2.7532 mL	13.7658 mL
20 mM	0.1377 mL	0.6883 mL	1.3766 mL	6.8829 mL
50 mM	0.0551 mL	0.2753 mL	0.5506 mL	2.7532 mL
100 mM	0.0275 mL	0.1377 mL	0.2753 mL	1.3766 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc